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Medchemexpress LLC Sch-1473759 hydrochloride | 1094067-13-6 | MFCD18251447 | 99.2% | 463.00 g/mol | C20H27ClN8OS | 200 MG
SDP

Supplier:  Medchemexpress LLC HY10483200MG

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SCH-1473759 hydrochloride is a small-molecule dual aurora kinase inhibitor used in research to probe cell-cycle regulation and kinase signaling. It potently inhibits Aurora A and Aurora B at low nanomolar concentrations and displays activity against several related kinases.

  • Potent dual Aurora A and B inhibition (IC50 = 4 nM and 13 nM).
  • Direct binding to Aurora kinases (Kd ≈ 20-30 nM).
  • Additional kinase activity including VEGFR2, Src family, Chk1, and IRAK4.
  • High purity (≈99.2%) and solid, white to yellow physical form.
  • Soluble in DMSO and water with warming; reported in vivo formulation options available.
  • Suitable for cell-cycle and kinase signaling research applications.
  • Recommended sealed storage; in solvent long-term storage at -80°C.

Catalog No. 50-002-43280


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