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Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML
Supplier: Medchemexpress LLC HY19545A10MM/1ML
SCH-23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. It is also a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM, and binds with high affinity to 5-HT2 and 5-HT1C receptors. It inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM. For research use only.
- Potent and selective dopamine D1-like receptor antagonist.
- Potent and high efficacy human 5-HT2C receptor agonist.
- Binds with high affinity to 5-HT2 and 5-HT1C receptors.
- Inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels.
- Used in studies of neurological disorders like psychosis and Parkinson's disease.
- Used in topographical determination of brain D1 receptors.
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