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Apexbio Technology LLC SCH 79797 dihydrochloride 1mg
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Supplier:  Apexbio Technology LLC B68011

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SCH 79797 dihydrochloride (CAS 1216720-69-2) is a potent and selective non-peptide antagonist of protease-activated receptor 1 (PAR1) It inhibits the binding of thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and displays a Ki of 35 nM for receptor modulation SCH 79797 dihydrochloride prevents thrombin-induced platelet aggregation with an IC50 of 3 M and demonstrates antiproliferative and pro-apoptotic effects as well as attenuation of myocardial ischemia/reperfusion injury The compound is utilized in biomedical research to study PAR1-mediated signaling in vascular smooth muscle cells endothelial cells and astrocytes

Catalog No. 50-000-91729


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