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Medchemexpress LLC Schisantherin A | 58546-56-8 | 151529 | 536.57 | 1 ML
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Catalog No. 5000416741
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Schisantherin A, also known as Gomisin-C, is a dibenzocyclooctadiene lignan. It inhibits p65-NF-κB translocation into the nucleus by IκBα degradation and has varied beneficial pharmacological effects, including anti-inflammatory properties and protection against acute respiratory distress syndrome.

  • Inhibits p65-NF-κB translocation into the nucleus
  • Decreases concentrations of TNF-α and IL-6
  • Reduces nitric oxide (NO) and prostaglandin E2 (PGE2) production
  • Exhibits anti-inflammatory properties by down-regulating NF-κB and MAPK signaling pathways
  • Protects against lipopolysaccharide-induced acute respiratory distress syndrome in mice
  • Shows antiproliferative activity against various human cancer cell lines

Catalog No. 50-004-16741 Supplier Medchemexpress LLC Supplier No. HYN069410MM/1ML
May include imposed supplier surcharges.
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Schisantherin A, also known as Gomisin-C, is a dibenzocyclooctadiene lignan. It inhibits p65-NF-κB translocation into the nucleus by IκBα degradation and has varied beneficial pharmacological effects, including anti-inflammatory properties and protection against acute respiratory distress syndrome.

  • Inhibits p65-NF-κB translocation into the nucleus
  • Decreases concentrations of TNF-α and IL-6
  • Reduces nitric oxide (NO) and prostaglandin E2 (PGE2) production
  • Exhibits anti-inflammatory properties by down-regulating NF-κB and MAPK signaling pathways
  • Protects against lipopolysaccharide-induced acute respiratory distress syndrome in mice
  • Shows antiproliferative activity against various human cancer cell lines

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