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Apexbio Technology LLC Scriptaid(Synonyms: Scriptaid, HDAC inhibitor Scriptaid, 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexanoic acid hydroxyamide), 10mM (in 1mL DMSO), CAS: 287383-59-9.
Supplier: Apexbio Technology LLC A41065.1
Scriptaid (CAS 287383-59-9) is a small-molecule histone deacetylase (HDAC) inhibitor originally identified through high-throughput transcriptional screening It specifically targets class I HDAC isoforms inhibiting HDAC1/HDAC3 and HDAC8 with IC50 values of approximately 0 6 M and 1 M respectively Structurally related to other hydroxamic acid-containing HDAC inhibitors such as TSA Scriptaid consists of a hydroxamic acid moiety a connecting linker and an aromatic cap group In glioblastoma (GBM) research Scriptaid shows promise by inducing apoptosis in glioma cells highlighting its potential utility for oncology-focused investigations
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