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Eurofins Discoverx Ready-to-Assay Secretin Glucagon Receptor Frozen Cells, 2 Vials of Cells. (HTS174RTA)

Catalog No. 502006006
Encompass

The Ready-to-Assay Secretin Glucagon Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses SCTR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of SCTR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.

Catalog No. 50-200-6006 Supplier Eurofins Discoverx Supplier No. HTS174RTA
May include imposed supplier surcharges.
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The Ready-to-Assay Secretin Glucagon Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses SCTR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of SCTR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.

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