Cayman Chemical Scutlar bac WogonsIde 25mg

Supplier:  Cayman Chemical 2933225 MG

A flavonoid with anti-inflammatory and anticancer activities; an active metabolite of wogonin; decreases colonic pathological damage and myeloperoxidase and iNOS activity, as well as inhibits NF-κB and NLRP3 inflammasome activation in a DSS-induced mouse model of colitis at 25 and 50 mg/kg; inhibits phosphorylation of mTOR, as well as inhibits the growth of (IC50 = 133.9 µM), and induces autophagy in, MDA-MB-231 breast cancer cells; inhibits tube formation by HUVECs, increases Wnt3a levels and β-catenin phosphorylation in MCF-7 cells at 50-100 µM; reduces tumor growth and angiogenesis in an MCF-7 mouse xenograft model at 80 mg/kg

Catalog No. 50-299-0004