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  6. Tocris Bioscience™ SEA 0400

Tocris Bioscience™ SEA 0400

Catalog No. 616410
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61-641-0 10 mg
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Catalog No. 61-641-0 Supplier Tocris Bioscience™ Supplier No. 6164/10
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Description

Potent Na+/Ca2+ exchanger (NCX) inhibitor.

SEA 0400 is a potent Na+/Ca2+ exchanger (NCX) inhibitor. Inhibits NCX activity in rat astrocytes, microglia and cultured neurons, canine cardiac sarcolemmal vesicles and rat cardiomyocytes (IC50 values are 5 and 8.3, 33, 90 and 92 nM, respectively). Reduces infarct volumes and exhibits protective effects against myocardial ischemia in rats.

Specifications

Product Type Inhibitor
Target Proteins Na+/Ca2+ Exchanger
CAS 223104-29-8
Molecular Formula C21H19F2NO3
Formula Weight 371.38g/mol
Content And Storage Store at -20°C
For Use With (Application) Na+/Ca2+ Exchanger Inhibitors
Quantity 10 mg

For Research Use Only

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