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Medchemexpress LLC Sec61-IN-1 | 2484865-42-9 | >99.7% | 430.53 | 50 MG
Supplier: Medchemexpress LLC HY13961550MG
Sec61-IN-1 is a potent sec61 inhibitor that effectively targets glioma cells and enhances T cell cytotoxic effects. It demonstrates efficacy in vitro by enhancing T cell cytotoxicity in U87 glioma cells and shows lower IC50 values in specific PDX cell lines. In vivo, it is detected in mouse brain tissue following intravenous injection, indicating potential for various research applications.
- Potent sec61 inhibitor
- Effectively targets glioma cells
- Enhances T cell cytotoxic effects in U87 glioma cells
- Lower IC50 for cytotoxicity in GBM12 and GBM38 PDX cell lines with SEC61G-EGFR dual amplification
- Detected in mouse brain tissue 45 min after intravenous injection
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