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Cayman Chemical SecurInIn 100mg
SDP

Supplier:  Cayman Chemical 24902100 MG

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An alkaloid; reduces proliferation of SW480 colon adenocarcinoma cells in a dose- and time-dependent manner; decreases viability of HL-60 leukemia cells (IC50s = 47.88, 23.85, and 18.87 μM at 24, 48, and 72 hours post-treatment, respectively); induces cell cycle arrest at the G1/S phase and decreases PI3K, Akt, and mTOR gene expression in a dose-dependent manner; inhibits GABA and GABA-activated benzodiazepine binding to rat brain membranes (IC50s = 57 and 101 μM, respectively); induces clonic and tonic convulsions in mice at 5.2 mg/kg

Catalog No. 50-301-5871


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