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Medchemexpress LLC Seltorexant hydrochloride | 1293284-49-7 | 99.9% | 443.91 | 50 MG
Supplier: Medchemexpress LLC HY109012A10MM/1ML
Seltorexant hydrochloride (JNJ-42847922 hydrochloride) is an orally active, high-affinity, and selective OX2R antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). It crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. It is for research use only.
- Orally active
- High-affinity and selective OX2R antagonist
- Crosses the blood-brain barrier
- Quickly occupies OX2R binding sites in the rat brain
- Dose-dependently induces and prolongs sleep in male Sprague-Dawley rats
- Sleep-promoting effects are maintained upon 7-day repeated dosing in rats
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