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AnaSpec SENSOLYTE 520 MMP ASSAY KITSE
Supplier: AnaSpec AS71158
SensoLyte 520 Generic MMP Activity Kit Fluorimetric, (1 kit) Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion as well as other diseases is well known. The SensoLyte 520 Generic MMP Assay Kit is optimized to detect the activity of a variety of MMPs, including MMP-1, 2, 3, 7, 8, 9, 12, 13, and 14. Compared to the SensoLyte 520 kits designed for individual MMP, the Generic MMP Assay kit is 5 to 20 fold more sensitive, although less specific. This kit is ideal for detecting generic MMP activity in biological samples or for high throughput screening of MMPs’ inducers and inhibitors using purified MMPs. This kit uses a 5-FAM (fluorophore) and QXL520(TM) (quencher) labeled FRET peptide substrates for continuous measurement of the enzyme activities (excitation/emission = 490 nm/520 nm)
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