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Cayman Chemical SEP-363856hydrochlorIde 100mg
SDP

Supplier:  Cayman Chemical 37399100 MG

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An inhibitor of ROCK2 (IC50 3.6 nM) selective for ROCK2 over PKC and CaMKII (IC50s 420 and 810 nM respectively) topical application reduces intraocular pressure in rabbit and cynomolgus monkeys at 0.05 v/v increases axonal regeneration at the crush site in a cat model of surgically-induced optic nerve damage at 10 and 100 UM inhibits demyelination and reduces the incidence of relapse episodes in a mouse model of chronic relapsing EAE

Catalog No. 50-291-8171


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