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Medchemexpress LLC Serotonin hydrochloride | 153-98-0 | 100.0% | 100 MG
SDP

Supplier:  Medchemexpress LLC HYB1473100MG

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Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter found in the Central Nervous System (CNS) and acts as an endogenous 5-HT receptor agonist, capable of crossing the blood-brain barrier. It also functions as a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.

  • Monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist
  • Exhibits blood-brain barrier permeability
  • Functions as a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM
  • Inhibits catechol O-methyltransferase (COMT) via non-competitive binding to the site bound by catechol substrates
  • Decreases the reaction velocity of COMT at a concentration of 100 μM
  • Produces robust hypersensitivity compared to saline-treated controls (p<0.001)

Catalog No. 50-004-11952


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