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Medchemexpress LLC Sertaconazole nitrate | 99592-39-9 | 99.2% | 100 MG
Supplier: Medchemexpress LLC HYB0736A100MG
Sertaconazole nitrate is a broad-spectrum topical antifungal agent that exhibits anti-inflammatory activity by activating a p38-COX-2-PGE2 pathway. It also acts as a microtubule inhibitor, demonstrating an antiproliferative effect, inducing apoptosis and autophagy, and inhibiting cell migration. This compound is widely used in research for its diverse biological activities.
- Inhibits 150 strains of yeasts, including six Candida species
- Exhibits anti-inflammatory activity by activating p38-COX-2-PGE2 pathway
- Induces strong mitotic arrest and antiproliferative effects
- Induces apoptosis through the p53 pathway
- Inhibits cell migration
- Induces autophagy in A549 and H460 cells
- Suppresses TPA-induced ear edema in vivo
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