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Cayman Chemical SertaconazolenItrate 100mg
SDP

Supplier:  Cayman Chemical 22232100 MG

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An imidazole antifungal agent; active against various yeasts, including C. albicans and C. tropicalis, and dermatophytes, including Microsporum, Trichophyton, and Epidermophyton (MICs = 0.35-5.04 and 0.24-2 UG/ml, respectively); inhibits ergosterol biosynthesis (IC50 = 115 nM) and decreases intracellular ATP levels in C. albicans; topical application reduces EAr edema induced by TPA, resiniferatoxin, or oxazolone in mouse models of irritant dermatitis, neurogenic dermatitis, and allergic contact hypersensitivity, respectively; selectively inhibits ACSL4 (IC50 = 0.28 µM) over ACSL3 at 50 µM; inhibits lipid peroxidation and ferroptosis induced by (1S,3R)-RSL3 in LUHMES cells at 5 µM

Catalog No. 50-298-7848


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