Wheaton glass containers are the choice for lyophilization. They excel in the 3 majors factors that contribute to successful Lyophillization: heat transfer, sealability, & water vapor transmission barrier. Heat Transfer–a Wheaton Glass serum vial, as opposed to glass serum bottles, plastic serum bottles, & other containers has a very consistent thin wall & bottom that allows the heating phase of the lyophilization process to take place rapidly & effectively. Sealability–Wheaton glass serum vials feature a inblowbackin feature in neck & bottom that allows for a 2 or 3 legged lyophilization stopper to be securely & evenly seated in the mouth of the vial. Water vapor Transmission Barrier–Wheaton glass serum vials are made from premium, low extractable, borosilicate glass, which offers a superior barrier to water vapors. Can be autoclaved, by dry heat, by chemical, by gas, or by radiation. Mfg from Wheaton in200in low extractable borosilicate glass tubing to hold uniform thickness.