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Medchemexpress LLC Sevabertinib (BAY 2927088) | 2521285-05-0 | 99.9% | 484.93 | 200 MG
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Supplier:  Medchemexpress LLC HY164718200MG

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Sevabertinib (BAY 2927088) is an orally active and reversible dual EGFR-HER2 inhibitor with potent anticancer activity against lung cancer. It shows significantly reduced activity against HER4.

  • Orally active and reversible dual EGFR-HER2 inhibitor
  • Exhibits anticancer activity against lung cancer
  • Potently inhibits proliferation of isogenic Ba/F3 cells ectopically expressing HER2 exon 20 insertions
  • Potently inhibits proliferation of isogenic Ba/F3 cells activating HER2 point mutations or putative secondary acquired resistance mutations
  • Inhibits proliferation of lung cancer cell lines NCI-H1781 and NCI-H2170

Catalog No. 50-003-91577


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