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Medchemexpress LLC Sevelamer hydrochloride | 152751-57-0 | 98.0% | 186.08 (monomer) | 5 G
Supplier: Medchemexpress LLC HY13995A5G
Sevelamer hydrochloride is an orally active phosphate binding agent primarily used for research related to hyperphosphatemia in chronic kidney disease. This compound consists of polyallylamine crosslinked with epichlorohydrin, and is intended for research use only, not for patient treatment.
- Orally active phosphate binding agent
- Used for research of hyperphosphatemia with chronic kidney disease
- Composed of polyallylamine crosslinked with epichlorohydrin
- Decreases serum levels of gut-derived uremic toxins (such as IAA) in vitro
- Reduces serum phosphate levels in Npt2b-deficient mice in vivo
- Leads to a significant decrease in osteoclast number in uremic WT mice
- Store at 4°C sealed, away from moisture for solid form
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