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Enzo Life Sciences SEW-2871 (50mg). CAS: 256414-75-2
Supplier: Enzo Life Sciences BMLLP1060050
SEW-2871 is a novel, potent EDG receptor agonist structurally unrelated to sphingosine-1-phosphate and is highly selective for the human S1P1 receptor. It inhibits lymphocyte recirculation in vivo and produces immunosuppression without associated bradycardia which is induced by other less selective S1P agonists. In mice SEW-2871 blocked TNFα induced monocyte adhesion to endothelium. Alternative name: 5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole. Purity: ≥98%. Long Term Storage: Ambient.
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