Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
ABclonal Technology SFT Rabbit mAb
Supplier: ABclonal Technology A21076100UL
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation Ubiquitination involves at least three classes of enzymes ubiquitin-activating enzymes or E1s ubiquitin-conjugating enzymes or E2s and ubiquitin-protein ligases or E3s This gene encodes a member of the E2 ubiquitin-conjugating enzyme family This enzyme is closely related to a stimulator of iron transport (SFT) and is up-regulated in hereditary hemochromatosis It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases Two transcript variants encoding different isoforms have been found for this gene
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?