Invitrogen™ Human SGK2, GST Tag Recombinant Protein

Catalog No.	Quantity
PV3858	10 μg

Catalog No. PV3858 Supplier Invitrogen™ Supplier No. PV3858

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Catalytic.

SGK2 is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Although little is known about the transcriptional regulation of SGK2, the protein has been shown to be phosphorylated and activated by 3 phosphoinositide dependent protein kinase 1 (PDK1), and to a lesser extent insulin like growth factor 1, in vitro.

Specifications

• Accession Number: Q9HBY8
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 2mM DTT, 50% glycerol, 0.5mM EDTA, 150mM NaCl, 0.02% Triton X-100 and no preservative; pH 7.5
• Gene ID (Entrez): 10110
• Molecular Weight (g/mol): 69.5 kDa
• Name: Human SGK2, GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: AI098171; AW146006; dJ138B7.2; H-SGK2; Serine/threonine-protein kinase Sgk2; serum/glucocorticoid regulated kinase 2; serum/glucocorticoid-regulated kinase 2; Sgk2; SGK2, serine/threonine kinase 2; Sgkl
• Common Name: SGK2
• Gene Symbol: SGK2
• Kinase Family: SGK Kinase Family
• Protein Length: aa 54-427
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: 54-427
• Content And Storage: Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
  Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Assay Entry: Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody)
• Kinase Group: Ser⁄Thr Kinases: AGC Group
• Shipping Condition: Dry Ice
• System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™, Omnia™ Bulk Substrate
• Target Entry: SGK2
• Target Gene: serum⁄glucocorticoid regulated kinase 2
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Catalytic
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Drug Discovery: Signal Transduction
• Purity or Quality Grade: 80% by SDS-PAGE