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Selleck Chemical LLC Shikonin 20mg 54952-43-1 Anchusin, Anchusa acid, Alkanna Red, C.I. 75535, Isoarnebin 4, NSC 252844

Supplier: Selleck Chemical LLC S827920MG
Shikonin (nchusin, Anchusa acid, Alkanna Red, C.I. 75535, Isoarnebin 4, NSC 252844), a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-? (TNF-?) and prevents activation of nuclear factor-?B (NF-?B) pathway via proteasome inhibition. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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