Cayman Chemical SHU9119 trifluoroacetate sal

Supplier:  Cayman Chemical 24152500 UG

An MC1R agonist and MC4R antagonist (IC50s = 1.2 and 2.9 nM, respectively, for displacement of melanocortin); induces cAMP formation in HEK293 cells expressing human MC1R (EC50 = 1.11 nM), but inhibits cAMP formation in cells expressing human MC4R; increases food intake, body weight, fat mass, and lean mass, with concomitant increases in blood glucose, insulin, and leptin levels via disrupted melanocortin signaling in rats (24 nmol, i.c.v. per day for seven days); increases in body weight and fat mass in mice

Catalog No. 50-293-4564