LifeSensors Ubiquitin Wild-type 5mg

Supplier:  LifeSensors SI02015000

ubiquitin is a small polypeptide that attaches via its C-terminus to lysine residues on target proteins. WT-Ubiquitin (wild-type) is the native, unmodified form and an essential tool for studying the ubiquitin-proteasome system (UPS), which controls protein degradation and turnover. It acts as the foundation for ubiquitin chains that signal for degradation or other cellular processes. WT-Ubiquitin is commonly used in assays involving E1, E2, and E3 enzymes, proteasome activity, polyubiquitin chain formation, and deubiquitinase (DUB) specificity. A single ubiquitin attachment is called monoubiquitylation, while additional ubiquitins linked through any of seven lysine residues form polyubiquitin chains. This tag-free recombinant human WT-Ubiquitin serves as a reference for modified variants and is critical for research into UPS-related diseases such as neurodegeneration, cancer, and immune disorders.

Catalog No. NC3710501