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Medchemexpress LLC SIC-19 | 713112-69-7 | 98.00% | 574.67 | 50 MG
Supplier: Medchemexpress LLC HY16374350MG
SIC-19 is an inhibitor of SIK2 (Salt-inducible Kinase 2) that promotes SIK2 protein degradation through the ubiquitination pathway. It inhibits cancer cell growth and increases the sensitivity of cells to PARP inhibitors, such as Olaparib. This effect has been observed in ovarian cancer organoids and xenograft models.
- Sik2 inhibitor
- Promotes SIK2 protein degradation via the ubiquitination pathway
- Inhibits cancer cell growth
- Sensitizes cells to PARP inhibitors
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