This Human Siglec-2/CD22 protein is a recombinant protein expressed from human 293 cells. As a member of the immunoglobulin superfamily and the SIGLEC family, it mediates B-cell interactions and acts as an inhibitory receptor. This low-endotoxin protein is suitable for various analytical applications, verified by SEC-MALS and SDS-PAGE.
- Greater than 95% purity as determined by SDS-PAGE and SEC-MALS.
- Contains a polyhistidine tag at the C-terminus.
- Calculated molecular weight of 77.0 kDa, migrating at 90-116 kDa due to glycosylation.
- Endotoxin level is less than 0.01 EU per μg.
- Lyophilized from a 0.22 μm filtered PBS solution, pH 7.4, containing trehalose as a protectant.
- Stable for 12 months at -20°C to -70°C in lyophilized state and 6 months at -70°C after reconstitution under sterile conditions.