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Sigma Aldrich Fine Chemicals Biosciences SigmaMAb Antibody Drug Con5MG
Supplier: Sigma Aldrich Fine Chemicals Biosciences MSQC80.5MG
SigmaMab Antibody Drug Conjugate (ADC) Mimic is a non-toxic drug mimic that is utilized as a standard for mass spectrometry and high performance liquid chromatography. The ADC Mimic conjugates SigmaMab (MSQC4) an IgG1 monoclonal antibody to dansyl fluorophores via an LC-SMCC crosslinker. This dansyl-LC-SMCC attachment serves as the substitution for the toxic payload of a real ADC. The ADC Mimic allows for safer and more consistent testing making it the optimal product over real ADCs. It is also a more affordable product compared to real ADCs. With the help of this non-toxic product LC-MS processes can be developed in a safer environment.
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