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Medchemexpress LLC Sildenafil | 139755-83-2 | C22H30N6O4S | 200 MG

Supplier: Medchemexpress LLC HY15025200MG
Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It demonstrates various cellular and in vivo activities, making it suitable for a range of research applications. This product is for research use only.
- Potent PDE5 inhibitor with an IC50 of 5.22 nM
- Inhibits human recombinant PDE5A1
- Potentiates ERK1/ERK2 phosphorylation
- Increases cell proliferation in S phase
- Significantly increases intracavernosal pressure (ICP) in dog models
- Reduces number of TL+-cells and microglia/macrophages in vivo
- Decreases flap necrosis in animal models by enhancing growth factor secretion
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