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Medchemexpress LLC Sildenafil | 139755-83-2 | MFCD00867528 | 99.99% | 474.58 | 100 MG
SDP

Supplier:  Medchemexpress LLC 100MGHY15025

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Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It has been shown to potentiate the phosphorylation of ERK1/ERK2, increase the percentage of cells in S phase, and enhance cell proliferation in vitro. In animal models, it significantly increases intracavernosal pressure and has been observed to decrease flap necrosis by increasing the secretion of growth factors.

  • Potent phosphodiesterase type 5 (PDE5) inhibitor.
  • Increases intracavernosal pressure.
  • Potentiates phosphorylation of ERK1/ERK2.
  • Increases cell proliferation.
  • Decreases flap necrosis by increasing growth factor secretion.

Catalog No. 50-003-64992


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