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Medchemexpress LLC Sildenafil citrate | 171599-83-0 | C28H38N6O11S | 1 G
SDP

Supplier:  Medchemexpress LLC HY15025A1G

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Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It is for research use only.

  • Potent phosphodiesterase type 5 (PDE5) inhibitor.
  • Potentiates phosphorylation of ERK1/ERK2 in vitro.
  • Increases percentage of cells in S phase and enhances cell proliferation in vitro.
  • Significantly increases intracavernosal pressure (ICP) in a dog model of erection in vivo.
  • Reduces the number of TL+-cells in vivo.
  • Decreases flap necrosis in preclinical animal models by increasing secretion of growth factors (FGF and VEGF).

Catalog No. 50-003-75473


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