Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Sildenafil (citrate) | 171599-83-0 | C28H38N6O11S | 5 G
Supplier: Medchemexpress LLC HY15025A5G
Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It is intended for research use only.
- Potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM.
- Potentiates phosphorylation of ERK1/ERK2.
- Increases percentage of cells in S phase and cell proliferation.
- Enhances upregulation of ERK1/ERK2 phosphorylation induced by serotonin.
- Increases intracavernosal pressure (ICP) and ICP/BP in dog models.
- Reduces the number of TL+-cells and microglia/macrophages in ischemic models.
- Decreases flap necrosis by increasing growth factors (FGF and VEGF).
- Used in clinical trials for pulmonary arterial hypertension, erectile dysfunction, spinal cord injuries, pregnancy complication, cancer, and more.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?