Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Sildenafil citrate | 171599-83-0 | MFCD09026931 | C22H30N6O4S ·C6H8O7 | 500 MG
Supplier: Medchemexpress LLC HY15025A500MG
Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It has demonstrated efficacy in potentiating the phosphorylation of ERK1/ERK2, promoting cell proliferation, and enhancing the upregulation of ERK1/ERK2 phosphorylation induced by serotonin in in vitro studies. In vivo, Sildenafil citrate has been shown to significantly increase intracavernosal pressure (ICP) and ICP/blood pressure (BP) in dog models of erection, and it has been reported to decrease flap necrosis in preclinical animal models.
- Potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM
- Potentiates ERK1/ERK2 phosphorylation in vitro
- Promotes cell proliferation and enhances ERK1/ERK2 phosphorylation induced by serotonin
- Increases intracavernosal pressure (ICP) and ICP/BP in dog models of erection
- Reported to decrease flap necrosis in preclinical animal models
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?