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Apexbio Technology LLC Sildenafil Citrate 171599-83-0 50mg
Supplier: Apexbio Technology LLC A432150
Sildenafil Citrate is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) PDE5 mediates degradation of cGMP a signaling molecule regulating smooth muscle tone vascular dilation and blood flow By inhibiting PDE5 Sildenafil Citrate elevates intracellular cGMP levels It has an IC50 value of approximately 3 6 nM against PDE5 Pharmacologically Sildenafil Citrate induces relaxation of smooth muscle tissues including penile corpus cavernosum and vascular smooth muscle thus facilitating increased blood flow It is widely utilized in biomedical research involving erectile dysfunction therapies and the management of pulmonary arterial hypertension (PAH)
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