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Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY50855B100MG

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Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor.

  • Causes cell-cycle arrest and selectively induces apoptosis in cancer cells by attenuating PI3K/Akt signaling.
  • Antiproliferative activity correlates with CK2α catalytic subunit expression.
  • Prevents leukemic cells from engaging UPR during PS-341 treatment, reducing BIP/Grp78 expression.
  • Induces cytotoxicity and apoptosis, exerting anti-proliferative effects in hematological tumors.
  • Demonstrates robust antitumor activity and reduces phospho-p21 (T145) in murine xenograft models.

Catalog No. 50-003-57913


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