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Bio X Cell InVivoSIM anti-human TNF (Infliximab Biosimilar), Human IgG1, 95% Purity, 5MG, 5 MG
Supplier: Bio X Cell SIM0006R005MG
This non-therapeutic biosimilar antibody utilizes the same variable regions as the therapeutic antibody Infliximab, making it suitable for research applications. It reacts with human TNF, a multifunctional proinflammatory cytokine. This biosimilar blocks the interaction of TNF with its receptors TNFR1 (p55) and TNFR2 (p75), down-regulating the inflammatory response associated with autoimmune diseases.
- Human IgG1 isotype
- Reacts w/ human TNF
- Immunogen: human TNF
- Endotoxin level 0.5 EU/mg
- Purity 95%
- Sterility via 0.2 m filtration
- Purified from cell culture supernatant in an animal-free facility
- Purification method: Protein A
- Formulated in PBS, pH 7.0, w/o stabilizers or preservatives
- Mol weight: 150 kDa
- Reported applications include in vitro TNF neutralization, in vitro functional assay, Flow Cytometry, ELISA, and Western Blot
- Store at stock concentration at 4C, do not freeze
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