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Bio X Cell Antibody, Human CTLA-4, Ipilimumab, IgG1, 1 MG
Supplier: Bio X Cell SIM0004R001MG
This non-therapeutic biosimilar antibody targets human CTLA-4 (cytotoxic T lymphocyte antigen-4), also known as CD152. Utilizing the identical variable regions as the therapeutic antibody Ipilimumab, it is suitable for research applications. CTLA-4 is a 33 kDa cell surface receptor found on activated T and B lymphocytes, negatively regulating cell-mediated immune responses. Ipilimumab blocks CTLA-4's inhibitory signal, enabling cytotoxic T cells.
- Clone: Ipilimumab
- Reactivities: Human
- Isotype: Human IgG1
- Conjugation: Unconjugated
- Immunogen: Human CTLA-4
- Formulation: PBS, pH 7.0 (no stabilizers or preservatives)
- Endotoxin level: ≤0.5EU/mg
- Purity: ≥95%
- Molecular weight: 150 kDa
- Storage: Store at 4°C, do not freeze
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