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Bio X Cell Anti-Human PD-1, Nivolumab Biosimilar, IgG4, 1 MG
Supplier: Bio X Cell SIM0003R001MG
This non-therapeutic biosimilar antibody utilizes the same variable regions as the therapeutic antibody Nivolumab, making it suitable for research applications. It is reactive with human PD-1 (programmed death-1), also identified as CD279. This humanized IgG4 monoclonal antibody is engineered with a hinge mutation (S228P) to minimize non-specific binding and enhance stability.
- Clone: Nivolumab
- Reactivity: Human
- Isotype: Human IgG4
- Mutations: S228P
- Formulation: PBS, pH 7.0 (no stabilizers/preservatives)
- Purity: ≥95% (SDS-PAGE)
- Production: Animal-free facility
- Purification: Protein A
- Endotoxin: ≤0.5 EU/mg
- Aggregation: <5%
- Sterility: 0.2 μm filtration
- Molecular weight: 150 kDa
- Storage: 4°C (do not freeze)
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