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Bio X Cell Antibody, Anti-human PD-1, IgG4, 5 MG
Supplier: Bio X Cell SIM0003R005MG
This non-therapeutic biosimilar antibody, derived from Nivolumab, reacts with human PD-1 (CD279). It is a humanized IgG4 monoclonal antibody engineered with a hinge mutation (S228P) to reduce non-specific binding and enhance stability for research applications.
- Isotype: Human IgG4; Immunogen: Human PD-1
- Formulation: PBS, pH 7.0; no stabilizers or preservatives
- Purity: ≥95%; Endotoxin: ≤0.5EU/mg; Aggregation: <5%
- Purification: Protein A; Molecular weight: 150 kDa
- Applications: In vitro PD-1 neutralization, in vivo PD-1/PD-L signaling blockade, functional assays, Flow Cytometry, IHC, Western Blot
- Storage: 4°C, do not freeze
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