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Bio X Cell InVivoSIM anti-human VEGFR-2, Ramucirumab Biosimilar, 50 MG
Supplier: Bio X Cell SIM0012R050MG
This non-therapeutic biosimilar antibody utilizes the same variable regions as the therapeutic antibody Ramucirumab. It interacts with human VEGFR-2, also known as CD309, KDR, and Flk-1, which is crucial for vascular development and permeability. Ramucirumab binds to the extracellular domain of VEGFR-2, inhibiting VEGF-mediated tumor angiogenesis.
- Clone: Ramucirumab
- Reactivities: Human
- Isotype: Human IgG1
- Conjugation: Unconjugated
- Immunogen: Human VEGFR2
- Reported applications: Functional assays, immunohistochemistry, flow cytometry
- Formulation: PBS, pH 7.0 (contains no stabilizers or preservatives)
- Endotoxin: ≤0.5EU/mg
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Molecular weight: 150 kDa
- Storage: Store at 4°C, do not freeze
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