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Medchemexpress LLC Simazine | 122-34-9 | 99.4% | 100 MG
Supplier: Medchemexpress LLC HYB2046100MG
Simazine is a triazine herbicide widely used in agriculture, potted plant, and tree production. It can induce apoptosis of immune cells in the spleen of mice and inhibit the proliferation of B cells and T cells in mice.
- Triazine herbicide
- Can inhibit maturation, disrupt spindle morphology, affect mitochondrial function, increase ROS levels, and induce DNA damage and early apoptosis of mouse oocytes
- Can lead to immunosuppression and immunotoxicity in mice
- Reduced proliferation of both spleen T and B cells in mice
- Decreased the number of spleen CD4+ T lymphocytes, while CD8+ T cells remained unchanged in mice
- Reduced immune function, higher intracellular [Ca2+], and oxidative stress in mice
- Induced spleen immune cell apoptosis by reducing Bcl-2, while increasing Fas and Caspase-3 levels in mice
- Appearance: Solid, white to off-white
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