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Medchemexpress LLC Simazine | 122-34-9 | 99.4% | 50 MG
Supplier: Medchemexpress LLC HYB204650MG
Simazine is a triazine herbicide widely used in agriculture, potted plant, and tree production. It can also induce apoptosis of immune cells in the spleen of mice and inhibit the proliferation of B cells and T cells in mice.
- Inhibits maturation and disrupts spindle morphology in mouse oocytes
- Affects mitochondrial function and increases ROS levels
- Induces DNA damage and early apoptosis of mouse oocytes
- Leads to immunosuppression and immunotoxicity in mice
- Reduces proliferation of spleen T and B cells
- Decreases numbers of spleen CD4+ T lymphocytes
- Reduces immune function and causes higher intracellular [Ca2+] and oxidative stress
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