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Apexbio Technology LLC Simeprevir(Synonyms: Olysio, TMC435, TMC435350, Simeprevir sodium), 10mM (in 1mL DMSO), CAS: 923604-59-5.
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Supplier:  Apexbio Technology LLC A38205.1

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Simeprevir (CAS 923604-59-5) is a small molecule inhibitor targeting the hepatitis C virus (HCV) NS3/4A protease a viral serine protease essential for viral polyprotein processing and replication Simeprevir inhibits NS3/4A protease with a Ki of 0 36 nM and demonstrates antiviral activity by reducing viral replication in Huh-7 replicon cells (EC50 of 7 8 nM) and Huh7-Luc HCV genotype 1b replicon cells (EC50 of 8 nM EC90 of 24 nM) Simeprevir is widely utilized in research on antiviral mechanisms and therapeutic strategies against HCV infections

Catalog No. 50-000-60909


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