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Medchemexpress LLC Simufilam hydrochloride | 2480226-07-9 | 99.9% | 295.81 | 10 MG
Supplier: Medchemexpress LLC 10MGHY139142B
Simufilam hydrochloride (PTI-125 hydrochloride) is an orally active FLNA modulator. It restores NMDAR signaling and Arc expression, inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, and reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation. It can be used for research of Alzheimer's disease.
- Acts as an orally active FLNA modulator
- Restores NMDAR signaling and Arc expression
- Inhibits overactive mTOR signaling by restoring normal FLNA conformation
- Improves insulin sensitivity
- Reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation
- Useful for Alzheimer's disease research
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