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AdipoGen Simvastatin . sodium salt (5 mg)
Supplier: AdipoGen AGCN20539M005
Chemical. CAS: 101314-97-0. Formula: C25H39O6 . Na. MW: 458.6. Synthetic analog of Lovastatin. Water-soluble carboxylate form of Simvastatin. Potent competitive HMG-CoA reductase inhibitor. Anti-hypercholesterolemic agent. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Inhibits the isoprenylation of Ras and Rho family GTPases. Smooth muscle cell proliferation inhibitor. Anti-adhesive, immunomodulatory and anti-inflammatory compound. Proteasome modulator. Stimulates bone formation. Apoptosis inducer. Anticancer compound. Increases cellular resistance to anticancer agents such as doxorubicin and etoposides. Suppresses ICAM-1-LFA-1 interactions, which blocks virus replication and infectio. Anti-hypertensive agent. Suppresses TNF-induced NF-kappaB activation.
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