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Medchemexpress LLC Sinapine (thiocyanate) | 7431-77-8 | 368.45 | 25 MG
Supplier: Medchemexpress LLC 25MGHYN0450
Sinapine thiocyanate is an alkaloid isolated from the seeds of cruciferous species. It exhibits various beneficial effects, including anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic, and radio-protective properties. It also acts as an acetylcholinesterase (AChE) inhibitor and is researched for its potential in treating neurological disorders such as Alzheimer's disease, ataxia, myasthenia gravis, and Parkinson's disease.
- Can counteract H2O2 and antimycin A-induced mitochondrial oxidative stress in cardiomyocytes.
- Inhibits the proliferation of Caco-2 cells in a dose-dependent manner and has relatively low toxicity.
- Promotes doxorubicin accumulation in Caco-2 cells by decreasing P-glycoprotein (P-gp).
- Reduces phosphorylation of FRS2α and ERK1/2.
- Reduces non-alcoholic fatty liver disease in mice by modulating the composition of the gut microbiota.
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