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Cayman Chemical SInfungIntrIfluoroacetate 10mg
Supplier: Cayman Chemical 4100410 MG
A purine nucleoside with diverse biological activities; inhibits G9a and SET7 (IC50s = 10.4 and 2.38 µM, respectively, using histone H3 (1-21) peptide as a substrate and IC50s = 150 and 9.1 µM, respectively, using full-length histone H3 as a substrate); inhibits PRMT5 (IC50s = 0.31 and 0.69 µM using histone H4 (1-21) peptide and full-length histone H4, respectively, as substrates); reduces renal fibrosis and H3K4me1 levels in a mouse model of unilateral ureteral obstruction at 10 mg/kg
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