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Medchemexpress LLC Sinomenine | 115-53-7 | C19H23NO4 | 100 MG

Supplier: Medchemexpress LLC HY15122100MG
Sinomenine is an alkaloid extracted from *Sinomenium acutum*. It functions as a blocker of NF-κB activation and also acts as an activator of the μ-opioid receptor.
- Source: extracted from the plant *Sinomenium acutum*.
- NF-κB blocker: inhibits NF-κB activation.
- Μ-Opioid receptor activator: activates the μ-opioid receptor.
- Antiproliferative activity: demonstrated antiproliferative activity against various human cancer cell lines, including K562.
- Anti-inflammatory and analgesic effects: shows anti-inflammatory activity, for instance, by inhibiting LPS-induced nitric oxide production in RAW264.7 cells. In rodents, it produces antinociception in hot plate and tail flick tests and reduces mechanical hypersensitivity in nerve-injured mice.
- Research use: primarily for research purposes.
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