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AdipoGen Sipholenol A (100 µg)

Supplier: AdipoGen AGCN20506C100
Chemical. CAS: 78518-73-7. Formula: C30H52O4. MW: 476.7. Isolated from marine sponge Siphonochalina siphonella. Efficient inhibitor of P-glycoprotein (Pgp, MDR-1) function through direct interactions. By inhibiting MDR-1, active compounds remain in the cytoplasm longer and allowing them to be more effective within the cell. Reversing agent for the treatment of multidrug resistance (MDR) in Pgp-overexpressing tumors. Potentiates the cytotoxicity of established P-gp substrates such as colchicine, vinblastine and paclitaxel. Antiproliferative and cytotoxic compound. Potent antifouling compound.
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