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Medchemexpress LLC Siramesine hydrochloride | 224177-60-0 | >99.69% | C30H32ClFN2O | 25 MG
SDP

Catalog No. 5000354689
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Siramesine hydrochloride is a potent sigma-2 receptor agonist, displaying subnanomolar affinity with an IC50 of 0.12 nM. It demonstrates high selectivity for sigma-2 receptors over sigma-1 receptors, with a 140-fold difference in IC50 values (17 nM for sigma-1). This compound induces cell death by destabilizing mitochondria and has shown anti-cancer activity.

  • Potent sigma-2 receptor agonist
  • High selectivity for sigma-2 over sigma-1 receptors
  • Triggers cell death through mitochondrial destabilization
  • Exhibits anti-cancer activity

Catalog No. 50-003-54689 Supplier Medchemexpress LLC Supplier No. 25MGHY14221A
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Siramesine hydrochloride is a potent sigma-2 receptor agonist, displaying subnanomolar affinity with an IC50 of 0.12 nM. It demonstrates high selectivity for sigma-2 receptors over sigma-1 receptors, with a 140-fold difference in IC50 values (17 nM for sigma-1). This compound induces cell death by destabilizing mitochondria and has shown anti-cancer activity.

  • Potent sigma-2 receptor agonist
  • High selectivity for sigma-2 over sigma-1 receptors
  • Triggers cell death through mitochondrial destabilization
  • Exhibits anti-cancer activity

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